Searchable abstracts of presentations at key conferences in endocrinology

ea0063gp218 | Gestational and Type 1 Diabetes | ECE2019

Effect of HbA1c and hyperglycemia on hemostasis in patients with type 1 diabetes

Sarkisova Karina , Jarek-Martynowa Iwona-Renata , Shestakova Marina , Chirkova Lydia , Nikankina Larisa , Shamkhalova Minara

Background and aims: Hyperglycemia can be a risk factor for adverse cardiovascular and cerebrovascular events. However, changes in platelets and coagulation hemostasis during hyperglycemia have not been extensively studied. The aim of this study was to assess the impact of level of fasting plasma glucose, HbA1c on the platelet activity, the physiological anticoagulant activity and fibrinolysis in patients with Diabetes Mellitus type 1 (DM1).Ma...

ea0056gp105 | Diabetes Translational | ECE2018

Acute insulin-induced hypoglycemia decreases systemic fibrinolytic balance in patients with type 1 diabetes

Sarkisova Karina , Jarek-Martynowa Iwona Renata , Shestakova Marina , Ilyin Alexander , Nikankina Larisa , Chirkova Lydia , Koksharova Ekaterina , Mishina Ekaterina , Shamkhalova Minara

Background and aims: Hypoglycemia can be a risk factor for adverse cardiovascular and cerebrovascular events. However, changes in platelets and coagulation hemostasis during hypoglycemia have not been extensively studied. During hypoglycemia, a wide spectrum of physiologic responses are activated that could have potential vascular biological effects. To date, the role played by catecholamines, the sympathetic nervous system, and neuroendocrine hormones on activating adhesion m...